Famke Janssen’s Career: From ‘Fathers & Sons’ to ‘Locked In’
Famke Janssen is a Dutch actress who has built a career playing strong, complex, and often unforgettable characters. After starting as a successful fashion model, she transitioned to acting and quickly made a name for herself with her striking presence and talent. She is widely recognized for major roles in blockbuster franchises, but her work also includes a variety of independent films and television series.
Janssen’s career is marked by her versatility and her ability to portray both heroes and villains with equal conviction. From a lethal Bond girl to a powerful mutant superhero, she has consistently chosen roles that are both challenging and memorable. This list highlights some of the key performances that have defined her journey in Hollywood, showcasing her range as an actress.
Fathers & Sons (1992)

Famke Janssen made her feature film debut in this crime drama. She played the character of Kyle Christian, the girlfriend of a mobster’s son. The film’s plot revolves around a beach community and the various conflicts that arise involving a local crime lord, his son, and a troubled film director.
This role was Janssen’s first step into the world of film after moving from modeling to acting. Although a small part in an independent movie, it was a crucial starting point that allowed her to gain experience and exposure. Her performance showcased the screen presence that would soon lead to much bigger and more prominent roles in major Hollywood productions.
GoldenEye (1995)

Janssen had her international breakout role as the villainous Xenia Onatopp in this James Bond film. Her character is a Georgian fighter pilot and a ruthless assassin who enjoys killing her victims by crushing them with her powerful thighs. She serves as a formidable and seductive henchwoman for the film’s main antagonist.
Her performance as Xenia Onatopp is one of the most memorable in the entire Bond series. Janssen perfectly captured the character’s mix of danger and allure, creating a true femme fatale for the modern era. The role instantly made her a household name and established her as a major new talent in Hollywood, opening the door for leading roles.
Deep Rising (1998)

Janssen plays Trillian St. James, a master jewel thief trapped on a luxury cruise liner. The ship is attacked in the middle of the South China Sea by giant, tentacled sea creatures from the deep ocean. She is forced to team up with the ship’s captain, played by Treat Williams, and a group of mercenaries to survive.
The film is a fun and fast-paced action-horror movie that has gained a significant cult following over the years. Janssen’s role as a cunning and capable thief was a departure from her femme fatale image in ‘GoldenEye’. She played a resourceful anti-hero, demonstrating her ability to hold her own in the action genre.
The Faculty (1998)

In this sci-fi horror film, Janssen plays Miss Elizabeth Burke, a timid and soft-spoken teacher at Herrington High School. She and other faculty members are taken over by alien parasites that are trying to conquer the world, starting with their school. Her character undergoes a dramatic transformation from shy to menacing.
Directed by Robert Rodriguez, ‘The Faculty’ became a teen horror classic of the 90s. Janssen’s performance was memorable for its stark contrast between her character’s initial personality and her later alien-controlled self. The role showed her versatility within the horror genre and cemented her place in a decade-defining cult favorite.
Rounders (1998)

In this cult classic film about the world of high-stakes poker, Janssen plays Petra, the manager of a New York poker club. She is a confidante and friend to the main character, Mike McDermott, played by Matt Damon. Petra is a steady, grounding presence in the often-chaotic underground poker scene.
While not a leading role, her part in ‘Rounders’ was significant. The film became hugely popular, especially among poker enthusiasts, and her character is a key part of the story’s atmosphere. Janssen brought a sense of warmth and intelligence to Petra, showing she could make a strong impression in a character-driven drama alongside a talented ensemble cast.
House on Haunted Hill (1999)

Janssen starred in this supernatural horror film, a remake of the classic movie. She plays Evelyn Stockard-Price, the cold and manipulative wife of an eccentric millionaire who offers a group of strangers money to spend a night in a haunted former asylum. Her character has her own sinister plans for the evening’s events.
The film was a commercial success at the box office and has since become a popular cult horror favorite. Janssen’s portrayal of the scheming and glamorous Evelyn was a standout performance. She excelled at playing a character who was both a potential victim and a villain, keeping the audience guessing about her true motives throughout the terrifying night.
X-Men (2000)

Janssen took on the iconic role of Dr. Jean Grey in the first film of the blockbuster ‘X-Men’ franchise. Jean is a powerful telepath and telekinetic, serving as the doctor for Professor Xavier’s school and a senior member of the X-Men. She is a compassionate figure who struggles to control the immense scale of her mutant abilities.
This role catapulted Janssen to a new level of fame. The ‘X-Men’ film was a massive critical and commercial success that helped launch the modern era of superhero movies. Her portrayal of Jean Grey was central to the series, and she would go on to reprise the role in several sequels, becoming a fan-favorite for her depiction of the complex and powerful character.
I Spy (2002)

Janssen stars as Special Agent Rachel Wright in this action-comedy, which is a modern adaptation of the classic TV series. She is a top secret agent who must team up with a bumbling civilian boxing champion, played by Eddie Murphy, and another agent, played by Owen Wilson. Their mission is to recover a stolen stealth fighter jet.
This big-budget film placed Janssen in the middle of a high-energy comedy, a different environment from her usual dramatic or thriller roles. She played the serious “straight man” to the comedic antics of Murphy and Wilson. While the film received mixed reviews, it showed she could hold her own in a major studio comedy.
Nip/Tuck (2004–2010)

Janssen took on a highly memorable recurring role in this edgy television drama about plastic surgeons. She played Ava Moore, a manipulative and seductive life coach who is revealed to be a transgender woman with a dark past and a disturbing relationship with her son. Her character’s storyline became one of the most talked-about arcs in the show’s history.
Her performance as Ava Moore earned Janssen widespread critical acclaim. She was praised for her brave and nuanced portrayal of a very complex and controversial character. The role demonstrated her incredible range and willingness to take on challenging material, creating one of television’s most unforgettable antagonists of the decade.
X-Men: The Last Stand (2006)

In the third installment of the ‘X-Men’ series, Janssen’s character, Jean Grey, is resurrected as the Phoenix. This new persona is an all-powerful and destructive force that threatens the entire world. The X-Men must confront their former friend and decide if she can be saved or if she must be stopped at any cost.
This film allowed Janssen to take center stage, exploring the darker, villainous side of her character. Her transformation from the heroic Jean Grey to the god-like Phoenix was the central plot of the movie. The role required a powerful and intense performance, and she delivered a memorable portrayal of a beloved comic book character’s tragic downfall.
Taken (2008)

Janssen plays Lenore “Lenny” Mills-St. John in this hugely successful action-thriller franchise. She is the ex-wife of former CIA operative Bryan Mills, played by Liam Neeson. The first film’s plot is set in motion when their daughter is kidnapped while on a trip to Paris, forcing Bryan to use his deadly skills to rescue her.
While her role is that of a supporting character, ‘Taken’ became a global phenomenon and spawned two sequels, making Janssen part of another major film franchise. She effectively portrays the concerned and often-conflicted mother, providing the emotional anchor for the film’s intense action. Her presence was a key element throughout the entire trilogy.
The Blacklist (2016–2018)

Janssen joined the cast of this popular crime thriller in a recurring role as Susan “Scottie” Hargrave. She is the brilliant and mysterious head of Halcyon Aegis, a covert mercenary organization that handles problems the government will not touch. Her character is introduced as both an antagonist and a potential ally.
Her character’s storyline was deeply connected to one of the show’s main characters, Tom Keen, revealing a complex and secret family history. Janssen’s portrayal of the powerful and morally grey Hargrave was so well-received by audiences that it led directly to her character getting her own spin-off series.
The Blacklist: Redemption (2017)

Janssen starred in this spin-off series to the popular show ‘The Blacklist’. She played Susan “Scottie” Hargrave, the head of a private military corporation that takes on dangerous missions. The show follows her team, including her estranged son Tom Keen, as they work to solve problems that are too risky for the government.
After being introduced in ‘The Blacklist’, Janssen’s character was popular enough to lead her own series. The role of Scottie Hargrave allowed her to be the powerful and morally ambiguous center of an action-packed show. It showcased her ability to lead a television series, playing a commanding character who is both a skilled operative and a mysterious mother.
Once Upon a Time in Venice (2017)

In this action-comedy, Janssen plays Katey Ford, the sister-in-law of the main character. The film follows Steve Ford, a down-on-his-luck private investigator played by Bruce Willis, whose life is turned upside down when his beloved dog is stolen. Janssen’s character gets caught up in his chaotic attempts to recover his pet.
The movie is a quirky and comedic take on the hard-boiled detective genre. Janssen’s role is a supporting one within a large ensemble cast that includes John Goodman and Jason Momoa. She provides a sense of the messy family life that exists in the background of the main character’s increasingly absurd adventure.
The Poison Rose (2019)

Janssen stars alongside John Travolta and Morgan Freeman in this neo-noir thriller. She plays Jayne Hunt, the former love of P.I. Carson Phillips, who returns to his hometown in Texas. He is hired to investigate a suspicious death, which leads him to uncover a web of crime and secrets involving the town’s most powerful figures, including Jayne.
This film saw Janssen take on the classic femme fatale role in a modern detective story. As Jayne, she is a glamorous and mysterious woman at the center of the film’s dark plot. Her performance adds to the movie’s traditional noir atmosphere, playing a character whose motives and loyalties are constantly in question.
The Postcard Killings (2020)

In this dark crime thriller, Janssen plays Valerie Kanon. The story follows a New York detective who travels to Europe after his daughter and son-in-law are brutally murdered. He discovers their deaths are part of a series of killings, and Janssen’s character is a German journalist whose child was also a victim.
Based on a novel by James Patterson, the film is a grim hunt for a serial killer. Janssen’s role is crucial, as she teams up with the main character, using her own grief and resources to help track down the killer. Her performance brings emotional weight to the tragic circumstances connecting the victims’ families.
Dangerous (2021)

In this action-thriller, Janssen plays Agent Shaughnessy. The story follows a reformed sociopath on parole who travels to a remote island after his brother’s death. He soon finds himself under siege by a group of mercenaries, and Janssen’s FBI agent character is investigating the complex situation.
The film is a straightforward action movie that features a cast of veteran actors. Janssen’s role as the determined federal agent is a supporting part, but it adds a layer of official investigation to the chaotic events. It’s another example of her work in the action and thriller genres, playing an authoritative figure.
Redeeming Love (2022)

Janssen appears as the Duchess in this historical romance set during the California Gold Rush. Based on the novel by Francine Rivers, the story follows a young woman named Angel who was sold into prostitution as a child. Janssen’s character is the cold and calculating madam who runs the brothel where Angel works.
This role saw Janssen playing a villainous character in a period drama setting. As the Duchess, she is a cruel and controlling figure in the protagonist’s life. The part, though not large, is critical to the main character’s backstory and her struggle for freedom and love.
Door Mouse (2023)

Janssen plays a character named Mama in this neo-noir thriller. The film centers on a young woman who works as a comic book artist and a dancer at a burlesque club. When one of her fellow dancers goes missing, she decides to investigate. Janssen’s character, Mama, is the tough owner of the club.
The film is a stylish independent thriller that explores dark and gritty themes. Janssen’s role as the world-weary but protective club owner is a key supporting performance. She adds a sense of authority and gravitas to the film’s unique setting, contributing to its noir atmosphere.
Knights of the Zodiac (2023)

In this fantasy action film based on a popular manga series, Janssen plays the main antagonist, Vander Guraad. Her character is the powerful and wealthy leader of a secret organization. She is hunting a young girl who is the reincarnation of the goddess Athena, hoping to destroy her before she can master her powers.
This role placed Janssen squarely back in the realm of big-budget, special-effects-driven blockbusters. As the film’s primary villain, she portrays a character with immense resources and a ruthless determination. Her performance is central to the conflict, providing the force against which the young heroes must unite.
Locked In (2023)

In this psychological thriller, Janssen plays Katherine, a former movie star who is left paralyzed and unable to speak after a severe accident. She is cared for by her daughter-in-law, Lina, but a nurse at the hospital suspects that Katherine’s condition may not be accidental. The story unfolds through flashbacks, revealing a dark web of secrets, betrayal, and murder.
This role required Janssen to act almost entirely with her eyes and facial expressions, a significant challenge for any performer. She effectively conveys fear, anger, and desperation without speaking, anchoring the film’s suspense. The part demonstrated her continued commitment to taking on complex and demanding roles late into her career.
Which Famke Janssen character do you find the most compelling, and why?


