Serena Williams Makes Headlines With Glp-1 Weight Loss Injection at Super Bowl
Serena Williams made headlines during the Super Bowl, but it wasn’t for her tennis skills. The 44-year-old legend appeared in a commercial for the telehealth company Ro, where she openly talked about using GLP-1 medication.
The ad, called Healthier on Ro, shows Williams discussing her weight loss journey and the progress she’s made over the past year. The 23-time Grand Slam winner revealed that she’s lost 34 pounds since starting Zepbound, a tirzepatide-based drug.
After the birth of her second daughter, Adira, in 2023, Williams said she struggled to shed extra pounds. “No matter what I did or how hard I trained, the scale wouldn’t budge,” she admitted.
She explained that the medication wasn’t about taking a shortcut. “It’s about fixing a metabolic problem that willpower alone couldn’t solve,” Williams said. She also noted that her cholesterol dropped by 30% and her heart disease risk is much lower. She joked on a recent podcast that her knees feel so good now she has “knees like Megan Thee Stallion.”
Her former coach, Patrick Mouratoglou, added perspective on her journey, recalling tough talks about weight during her competitive years. “I pushed her because I knew the physical toll of competing at the highest level while carrying extra weight,” he said. For Williams, reaching a weight where she feels energized has been deeply personal.
Serena Williams injects herself with a GLP-1 weight loss drug as millions watch the Super Bowl.
— Vigilant Fox 🦊 (@VigilantFox) February 9, 2026
She dances and shows off how “convenient” it is to get GLP-1s using the Ro app.
She even says you can get them in pill form.
I miss the days when the Super Bowl sold beer & trucks.… pic.twitter.com/snXlyGHZfS
Off the court, Williams is busier than ever. She’s preparing for the February 23 premiere of her Prime Video docuseries, The CEO Club, which she also executive-produced. The eight-part series follows Williams and other female leaders navigating the challenges of entrepreneurship and global business.
She’s also working as an executive producer on Netflix’s adaptation of Taylor Jenkins Reid’s novel, Carrie Soto Is Back. The story follows a retired tennis player returning to defend her record—a plot that has sparked rumors about Williams’ own potential comeback. She recently teased on The Today Show, saying “we’ll see” about returning to tennis, but currently lists her official occupation as housewife.
Beyond media, Williams leads Serena Ventures, her venture capital firm focused on funding companies founded by women and people of color. She continues to use her platform to inspire and support others.
Do you think Serena Williams talking openly about medical weight loss will help reduce stigma for others, or should athletes stick to traditional diet and exercise? Share your thoughts in the comments.
