'Harley Quinn' #49 Preview: An Unlikely Friendship Is Formed

Harley Quinn’s popularity has been growing steadily in recent years, and we can confirm that she is now one of DC’s most popular assets. The quirky sidekick became a standalone villainess or antiheroine, beloved by many fans around the world.

As you probably know, Harley Quinn has also been the focus of numerous stories currently, including an ongoing solo series. In this report, we are going to provide you with a proper preview of the upcoming Harley Quinn #49, which is set to come out on March 26, 2025.

Written by Eliott Kalan, with art by Mindy Lee, Harley Quinn #49 is going to continue the story and focus on Harley’s new friendship with a very unlikely character – Amygdala. Here is what the synopsis reveals:

HARLEY HANGS WITH AMYGDALA! This issue is chock-full of my pal Amygdala, so I’ve asked him to tell you about it in his own words: Rich lady tell Amygdala hit clown lady. Amygdala hit clown lady. Clown lady hit Amygdala on head but he not feel owie. Amygdala hit back. Bad dogs bite Amygdala too but no feel owie. Everyone fight. You buy?

As for the preview images, here they are: