‘The Apothecary Diaries’ Season 2, Cour 2 Reveals Trailer and New Information

Ever since the anime’s 2023 premiere, The Apothecary Diaries series has been an enormous hit. The anime helped the original series grow, and the adaptation was one of the best ones in recent years, with the fans appreciating the animation, as well as the story and characters.

The second season of the anime is currently airing and its first cour ended today, on March 28, 2025, after 12 episodes. Now, the series is getting ready for the second cour, which will premiere on April 4, 2025.

Before we continue, here is the trailer:

Alongside the new visuals and plot elements, the video also previews the new opening theme song “Kusuhiki” (Mysterious) by Mrs. Green Apple and the new ending theme song “Hitorigoto” (Soliloquy) by Omoinotake, whose exceprts you can listen to here.

As said, the second cour premiered on April 4, 2025. In case you don’t know what the series is about, here is a short synopsis:

In the East is a land ruled by an emperor, whose consorts and serving women live in a sprawling complex known as the hougong, the rear palace. Maomao, an unassuming girl raised in an unassuming town by her apothecary father, never imagined the rear palace would have anything to do with her—until she was kidnapped and sold into service there.

Though she looks ordinary, Maomao has a quick wit, a sharp mind, and an extensive knowledge of medicine. That’s her secret, until she encounters a resident of the palace at least as perceptive as she is: the head eunuch, Jinshi. He sees through Maomao’s façade and makes her a lady-in-waiting to none other than the Emperor’s favorite consort… so she can taste the lady’s food for poison!

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