Actresses Who Had Serious Health Problems
The world of professional entertainment often masks the physical and mental health challenges faced by its biggest stars. Many famous actresses have managed serious chronic illnesses and life threatening conditions while working in the spotlight. These individuals use their platforms to raise awareness and provide hope for others dealing with similar medical issues. From autoimmune diseases to cancer battles, their stories highlight the resilience required to thrive in a demanding industry. This list examines the health journeys of prominent women in the acting world.
Selena Gomez

Selena Gomez went public with her lupus diagnosis which eventually required her to undergo a kidney transplant. The actress received the organ from her close friend after experiencing complications from the autoimmune disease. She has also been transparent about her journey with bipolar disorder and mental health management. Gomez continues to act in the popular series ‘Only Murders in the Building’ while advocating for medical research. Her story has inspired many people to seek help and support for chronic conditions.
Christina Applegate

Christina Applegate was diagnosed with multiple sclerosis during the production of her final season of ‘Dead to Me’. The actress had previously faced a battle with breast cancer which led to a double mastectomy. She has spoken candidly about the mobility challenges and physical pain associated with her neurological condition. Applegate often uses a cane during public appearances to help with her balance and stability. She remains a strong advocate for others living with invisible illnesses.
Shannen Doherty

Shannen Doherty fought a long and very public battle with stage four breast cancer for several years. The ‘Charmed’ star first announced her diagnosis in 2015 and underwent various treatments including chemotherapy and surgery. She was also known to live with Crohn’s disease which she managed throughout her career. Doherty documented her health journey on social media to provide an honest look at the realities of cancer treatment. Her bravery in the face of terminal illness left a lasting impact on her fans and colleagues.
Emilia Clarke

Emilia Clarke survived two life threatening brain aneurysms while filming the hit series ‘Game of Thrones’. The first incident occurred shortly after the first season finished production and required immediate surgery. She suffered a second aneurysm a few years later that resulted in a more difficult recovery process. Clarke eventually launched a charity called SameYou to support neurorehabilitation for young people. She has expressed deep gratitude for the medical teams that saved her life during those critical years.
Sarah Hyland

Sarah Hyland was born with kidney dysplasia and has undergone two kidney transplants throughout her life. The ‘Modern Family’ actress received her first transplant from her father and a second one from her brother after the first failed. She has endured over sixteen surgeries and numerous hospitalizations to manage her health. Hyland has been vocal about the mental toll of chronic illness and the importance of family support. She continues to work in the industry while prioritizing her ongoing medical needs.
Jada Pinkett Smith

Jada Pinkett Smith revealed her struggle with alopecia which causes significant hair loss. The actress shared her diagnosis on ‘Red Table Talk’ after fans noticed her wearing turbans and close cropped hairstyles. She has discussed the emotional difficulty of losing her hair and the process of accepting her new appearance. Smith uses her platform to educate the public about the autoimmune condition and reduce the stigma surrounding it. Her transparency has helped many women facing similar hair loss issues feel more confident.
Jamie-Lynn Sigler

Jamie-Lynn Sigler lived with multiple sclerosis in secret for fifteen years before going public with the news. The ‘The Sopranos’ star was diagnosed at age twenty but feared the news would end her acting career. She eventually decided to share her story to help others and explain her physical limitations on set. Sigler manages her symptoms with medication and careful lifestyle adjustments to maintain her busy schedule. She now works closely with organizations to fund research and support for the MS community.
Lena Dunham

Lena Dunham has dealt with severe endometriosis for most of her adult life. The creator and star of ‘Girls’ underwent a total hysterectomy at age thirty one to alleviate the chronic pain. She has detailed the multiple surgeries and hospital visits required to manage the reproductive health condition. Dunham wrote extensively about her medical journey to raise awareness for women experiencing similar pain. Her openness has sparked important conversations about the need for better diagnostic tools for endometriosis.
Amy Schumer

Amy Schumer was diagnosed with Cushing’s syndrome after fans pointed out changes in her facial appearance. The actress also suffers from severe endometriosis and underwent surgery to remove her uterus and appendix. During her pregnancy, she faced hyperemesis gravidarum which caused extreme nausea and frequent hospitalizations. Schumer discussed these issues in her documentary ‘Expecting Amy’ to show the raw reality of her health struggles. She continues to use humor to address the various medical hurdles she has faced.
Lady Gaga

Lady Gaga lives with fibromyalgia which causes chronic widespread pain and significant fatigue. The star of ‘A Star Is Born’ has had to cancel concert dates and postpone projects due to intense physical flare ups. She featured her struggle with the condition in the documentary ‘Gage: Five Foot Two’ to provide a glimpse into her daily life. Gaga utilizes various therapies including massage and heat treatment to manage the symptoms of the condition. She remains dedicated to her craft while being mindful of her physical limitations.
Julia Louis-Dreyfus

Julia Louis-Dreyfus announced her breast cancer diagnosis just one day after winning an Emmy for ‘Veep’. She underwent six rounds of chemotherapy and a double mastectomy during her treatment process. The actress used social media to update fans on her progress with a mix of honesty and trademark humor. After completing her treatment, she returned to work and successfully finished the final season of her hit show. She now advocates for universal healthcare and support for cancer survivors.
Kathy Bates

Kathy Bates is a two time cancer survivor who has overcome both ovarian and breast cancer. Following her double mastectomy, she developed lymphedema which causes painful swelling in her arms. The ‘Misery’ actress now serves as a spokesperson for the Lymphatic Education and Research Network. She has spoken about the lack of awareness regarding lymphedema and the physical challenges it presents. Bates continues to deliver powerful performances while managing the chronic swelling in her limbs.
Fran Drescher

Fran Drescher survived uterine cancer after being misdiagnosed by several doctors over a two year period. The star of ‘The Nanny’ wrote a book titled ‘Cancer Schmancer’ to detail her experiences with the healthcare system. She later founded an organization of the same name to focus on early detection and women’s health. Drescher emphasizes the importance of patients being their own advocates and seeking second opinions. She has been in remission for over two decades and remains a prominent health activist.
Olivia Newton-John

Olivia Newton-John lived with breast cancer for thirty years after her initial diagnosis in 1992. The ‘Grease’ star became a global symbol of hope as she navigated multiple recurrences of the disease. She established the Olivia Newton-John Cancer Wellness and Research Centre in Australia to help others. Throughout her journey, she advocated for the use of plant based medicine and holistic therapies alongside traditional treatments. Her legacy continues to inspire cancer research and patient care worldwide.
Angelina Jolie

Angelina Jolie made the difficult decision to undergo a preventive double mastectomy after discovering she carried the BRCA1 gene. The ‘Maleficent’ actress had a high genetic risk of developing both breast and ovarian cancer. She later had her ovaries and fallopian tubes removed to further reduce her health risks. Jolie wrote a public piece for the ‘New York Times’ to explain her choice and encourage other women to explore their medical options. Her transparency led to a significant increase in genetic testing for cancer risks.
Rita Wilson

Rita Wilson was diagnosed with invasive lobular carcinoma and underwent a double mastectomy for breast cancer treatment. The actress and singer sought a second opinion which was crucial in identifying the correct diagnosis. She has credited her recovery to early detection and the support of her husband Tom Hanks. Wilson has appeared in films like ‘Sleepless in Seattle’ and continues to produce successful projects in Hollywood. She encourages all women to trust their instincts and seek additional medical advice when necessary.
Wanda Sykes

Wanda Sykes discovered she had ductal carcinoma in situ during a breast reduction surgery. The comedian and actress chose to have a bilateral mastectomy to eliminate the risk of the cancer returning. She spoke about her diagnosis during an appearance on ‘The Ellen DeGeneres Show’ to share her experience with humor. Sykes mentioned that her family history played a large role in her decision to pursue aggressive treatment. She remains cancer free and active in the entertainment industry.
Céline Dion

Celine Dion revealed she was diagnosed with Stiff Person Syndrome which is a rare neurological disorder. The legendary singer and actress had to cancel her world tour as the condition affects her ability to walk and sing. The disorder causes severe muscle spasms and stiffness throughout the body. Dion has shared her journey in a documentary titled ‘I Am: Celine Dion’ to educate the public about the condition. She is currently working with a dedicated medical team to regain her strength and return to the stage.
Catherine Zeta-Jones

Catherine Zeta-Jones sought treatment for Bipolar II disorder following a period of high stress. The actress decided to go public with her mental health diagnosis to help de-stigmatize the condition. She has starred in major films like ‘Chicago’ and ‘Traffic’ while managing her symptoms through professional care. Zeta-Jones emphasizes that there is no shame in seeking help for mental health issues. Her openness has been praised for encouraging others to prioritize their psychological well being.
Sharon Stone

Sharon Stone suffered a massive stroke and a nine day brain bleed in 2001 that nearly cost her her life. The ‘Basic Instinct’ star had to relearn basic skills including walking, talking, and reading during a long recovery. She has spoken about how the health crisis caused her to lose her career and position in Hollywood for several years. Stone now works to raise awareness for brain health and the signs of stroke in women. She has successfully returned to acting and remains a prominent figure in the industry.
Toni Braxton

Toni Braxton was diagnosed with systemic lupus erythematosus which is a serious autoimmune disease. The singer and ‘Braxton Family Values’ star has been hospitalized multiple times due to complications from the illness. She has discussed the difficulty of performing while dealing with extreme fatigue and heart issues related to lupus. Braxton continues to manage her condition while pursuing her music and acting career. She is a dedicated supporter of lupus research and often speaks at awareness events.
Gigi Hadid

Gigi Hadid manages Hashimoto’s disease which is an autoimmune disorder that affects the thyroid gland. The actress and model has addressed her fluctuating weight in response to public criticism about her appearance. She explained that her metabolism changed significantly due to the medication and the disease itself. Hadid focuses on a balanced diet and specific exercise routines to keep her energy levels stable. She remains one of the most successful figures in the fashion and entertainment worlds.
Sia

Sia has lived with chronic physical pain caused by Ehlers Danlos syndrome and a neurological disease. The singer and ‘Music’ director has often spoken about her health struggles on social media to connect with fans. She deals with symptoms like joint hypermobility and extreme exhaustion which can make working difficult. Sia has been open about her past struggles with addiction and how they were tied to her physical suffering. She continues to create art while navigating the complexities of her chronic conditions.
Halle Berry

Halle Berry was diagnosed with diabetes at the age of twenty two after falling into a coma on a television set. The ‘Monster’s Ball’ star has managed the condition for decades through strict diet and regular exercise. She has often spoken about how the diagnosis forced her to become more health conscious and disciplined. Berry remains one of the most fit and active actresses in Hollywood despite the daily requirements of her condition. She continues to inspire others by showing that a chronic diagnosis does not limit success.
Sheryl Crow

Sheryl Crow was diagnosed with breast cancer in 2006 and underwent a successful lumpectomy and radiation treatment. Years later she discovered she had a benign brain tumor called a meningioma after experiencing memory loss. The musician and actress has remained vigilant about her health and encourages regular screenings. She has used her experiences to advocate for environmental health and cancer research funding. Crow remains active in both the music and film industries while maintaining a healthy lifestyle.
Cynthia Nixon

Cynthia Nixon kept her breast cancer diagnosis a secret for several years before sharing it with the public. The ‘Sex and the City’ star chose to reveal her journey once she became an official spokesperson for a cancer foundation. Her mother had also survived the disease which prompted Nixon to be diligent about her annual mammograms. She underwent a lumpectomy and radiation to treat the illness successfully. Nixon now uses her political and acting platforms to fight for better healthcare access.
Edie Falco

Edie Falco was diagnosed with breast cancer while she was starring in the hit series ‘The Sopranos’. She decided to keep the news private during her treatment to avoid public scrutiny and focus on her work. Falco underwent chemotherapy and has been in remission for many years. She has credited her sobriety and healthy lifestyle for helping her through the difficult recovery process. The actress remains a celebrated figure in television and a vocal supporter of cancer awareness.
Maggie Smith

Maggie Smith was diagnosed with breast cancer during the filming of ‘Harry Potter and the Half Blood Prince’. Despite undergoing grueling chemotherapy treatments, she insisted on continuing her work on the film set. The legendary actress wore a wig and pushed through extreme exhaustion to complete her scenes. She eventually made a full recovery and continued her award winning career in ‘Downton Abbey’. Smith’s dedication to her craft during such a difficult time is widely admired by her peers.
Jane Fonda

Jane Fonda has survived several different forms of cancer including skin cancer and breast cancer. In recent years she announced she was diagnosed with non Hodgkin lymphoma and began chemotherapy treatments. The iconic actress and activist maintained a positive outlook and continued her climate change protests during her recovery. She eventually shared the good news that her cancer was in remission. Fonda continues to work on major projects like ‘Grace and Frankie’ while staying active in social causes.
Marcia Cross

Marcia Cross was diagnosed with anal cancer and underwent a difficult course of radiation and chemotherapy. The ‘Desperate Housewives’ star decided to speak openly about her specific type of cancer to break the stigma surrounding it. She has emphasized that the disease is often caused by the human papillomavirus and encourages vaccination. Cross has been in remission for several years and frequently shares health tips with her followers. She remains an advocate for transparency regarding often misunderstood medical conditions.
Cobie Smulders

Cobie Smulders was diagnosed with ovarian cancer at the age of twenty five while filming ‘How I Met Your Mother’. She underwent multiple surgeries over the course of two years to remove the cancerous tissue. Smulders kept her struggle private for years before deciding to share her story in a magazine interview. She has since welcomed two children despite initial fears that the surgeries would impact her fertility. The actress continues to star in major franchises like the Marvel Cinematic Universe.
Sharon Osbourne

Sharon Osbourne battled colon cancer which eventually spread to her lymph nodes during her time on ‘The Osbournes’. She underwent a series of surgeries and chemotherapy that were documented on her reality show. Years later she also chose to have a double mastectomy after discovering she carried a gene for breast cancer. Osbourne has been very vocal about her health journey and the importance of early screening for colon health. She remains a prominent television personality and manager in the entertainment industry.
Mary-Kate Olsen

Mary-Kate Olsen sought professional help for an eating disorder during the height of her teen stardom. The actress and fashion mogul entered a treatment facility to address the serious health condition. She has since moved away from acting to focus on her successful fashion brands with her sister. Olsen has rarely spoken about the experience in detail but has emphasized the importance of privacy during recovery. Her journey highlighted the immense pressure faced by young women in the spotlight.
Zoe Saldaña

Zoe Saldana lives with Hashimoto’s disease which is an autoimmune condition that affects her thyroid. The ‘Avatar’ star follows a strict gluten free and dairy free diet to help manage the symptoms of the disorder. She has spoken about how the condition can cause significant fatigue and requires her to monitor her health closely. Both her mother and sisters also deal with the same condition which provides her with a strong support system. Saldana remains one of the highest grossing actresses in film history despite these challenges.
Victoria Beckham

Victoria Beckham has lived with polycystic ovary syndrome which is a condition that can affect fertility and hormone levels. The actress and designer has discussed the difficulties she faced when trying to conceive her children. She has been open about the importance of a healthy diet and lifestyle in managing the symptoms of the disorder. Beckham continues to be a major force in the fashion world while raising her four children. Her transparency has helped other women feel more comfortable discussing reproductive health issues.
Daisy Ridley

Daisy Ridley was diagnosed with endometriosis and polycystic ovary syndrome when she was a teenager. The ‘Star Wars’ actress shared her health journey on social media to explain the physical and emotional toll of the conditions. She recently revealed that she was also diagnosed with Graves disease which is an autoimmune disorder affecting the thyroid. Ridley manages her health through various treatments and a focus on self care. She continues to take on demanding physical roles while staying mindful of her medical needs.
Amy Brenneman

Amy Brenneman suffered from severe ulcerative colitis which eventually required her to undergo several major surgeries. The ‘Private Practice’ star had her large intestine removed to save her life after traditional treatments failed. She has spoken candidly about the challenges of living with a chronic digestive illness while working in television. Brenneman is now a spokesperson for the Crohn’s and Colitis Foundation to support others with similar diagnoses. She remains a successful actress and producer in the Hollywood community.
Kim Kardashian

Kim Kardashian has lived with psoriasis for many years and frequently shares her flare ups with her followers. During her pregnancies she also suffered from preeclampsia and placenta accreta which are life threatening conditions. These medical issues led her to use a surrogate for her third and fourth children to avoid further health risks. Kardashian has used her television show to document her medical appointments and treatments. She continues to build her business empire while managing these chronic and situational health problems.
Tia Mowry

Tia Mowry has been an advocate for endometriosis awareness after struggling with the condition for years. The ‘Sister, Sister’ actress underwent multiple surgeries and changed her diet to manage the chronic pain and fertility issues. She has written books and shared recipes that focus on anti inflammatory eating to help others with the disorder. Mowry credits her lifestyle changes with helping her successfully conceive her two children. She remains a popular figure in television and a prominent voice in the wellness community.
Gabrielle Union

Gabrielle Union suffered from adenomyosis which caused years of physical pain and multiple miscarriages. The ‘Bring It On’ actress shared her journey in her memoir to shed light on the difficulties of infertility and reproductive health. She eventually welcomed her daughter via surrogate after realizing the toll the condition had taken on her body. Union uses her platform to support women of color who often face disparities in medical treatment. She remains a highly successful actress and advocate for social justice and health equity.
Sofía Vergara

Sofia Vergara was diagnosed with thyroid cancer at the age of twenty eight after a doctor discovered a lump in her neck. She underwent surgery to remove her thyroid gland and followed it with iodine radiation treatment. The ‘Modern Family’ star has to take daily medication to regulate her metabolism for the rest of her life. Vergara has spoken about how the experience made her realize the importance of regular health checkups. She is now one of the most successful and highest paid actresses in television history.
Elisabeth Hasselbeck

Elisabeth Hasselbeck lived with undiagnosed celiac disease for many years before finally receiving a correct diagnosis. The actress and television host suffered from chronic pain and fatigue during her time on ‘Survivor’. She eventually wrote a book about her experience to help others identify the symptoms of gluten intolerance. Hasselbeck has become a major advocate for the gluten free community and nutritional awareness. She continues to work in media while maintaining a strict diet to keep her symptoms in check.
Brooke Shields

Brooke Shields struggled with severe postpartum depression after the birth of her first daughter. The actress and model wrote a book titled ‘Down Came the Rain’ to detail her experience and the help she received. She faced public criticism for her use of medication but remained firm in her decision to speak out. Her honesty helped bring national attention to a condition that many women face in silence. Shields remains a respected figure in the industry and continues to advocate for maternal mental health.
Elizabeth Taylor

Elizabeth Taylor faced numerous health crises throughout her legendary career including a brain tumor and congestive heart failure. She underwent over one hundred surgeries during her lifetime and survived multiple bouts of pneumonia. The iconic actress used her experiences with illness to fuel her passion for philanthropy and medical research. She became a leading figure in the fight against HIV and AIDS when few others would speak up. Taylor’s resilience in the face of constant physical challenges remains a testament to her strength.
Audrey Hepburn

Audrey Hepburn was diagnosed with a rare form of abdominal cancer known as pseudomyxoma peritonei later in her life. The beloved actress and humanitarian underwent surgery and chemotherapy but the disease was very advanced. She spent her final months at her home in Switzerland surrounded by her family and close friends. Hepburn is remembered not only for her classic films like ‘Breakfast at Tiffany’s’ but also for her extensive work with UNICEF. Her grace and dedication to helping others continued until the very end of her life.
Jennifer Grey

Jennifer Grey suffered a severe neck injury in a car accident just before the release of ‘Dirty Dancing’. The injury caused chronic pain that lasted for decades and eventually required complex spinal surgery. During her medical evaluations she also discovered a cancerous nodule on her thyroid which was successfully removed. Grey eventually returned to the spotlight and won a season of ‘Dancing with the Stars’ after her recovery. She has spoken about the relief of finally living without the constant physical pain she endured for years.
Padma Lakshmi

Padma Lakshmi lived with undiagnosed endometriosis for over two decades before receiving a proper diagnosis. The actress and ‘Top Chef’ host underwent several surgeries to manage the condition which had severely impacted her quality of life. She cofounded the Endometriosis Foundation of America to raise awareness and fund research for the disease. Lakshmi has been vocal about the need for doctors to take women’s pain more seriously during medical consultations. She continues to be a leading voice in both the culinary and entertainment worlds.
Mischa Barton

Mischa Barton has been open about her struggles with mental health and the pressures of early fame. The ‘The O.C.’ star was placed under an involuntary psychiatric hold during a particularly difficult period in her life. She has since spoken about the importance of seeking professional help and the challenges of recovering in the public eye. Barton has worked to rebuild her career and has appeared in various independent films and television projects. Her story highlights the need for better mental health support for young performers in Hollywood.
Gwyneth Paltrow

Gwyneth Paltrow discovered she had osteopenia which is a precursor to osteoporosis after suffering a severe leg fracture. The actress and entrepreneur also faced a difficult period of postpartum depression following the birth of her second child. She has utilized her wellness platform to share her health findings and the lifestyle changes she made to improve her bone density. Paltrow remains a polarizing but influential figure in the health and wellness industry. She continues to act in major film franchises while managing her various business ventures.
Whoopi Goldberg

Whoopi Goldberg faced a near fatal battle with double pneumonia and sepsis that kept her away from her hosting duties. The legendary actress and comedian was hospitalized for several weeks as doctors worked to stabilize her condition. She has spoken about how close she came to losing her life and the slow process of recovery. Goldberg has used her experience to remind her audience about the importance of taking respiratory health seriously. She eventually returned to her professional roles with a new perspective on the value of her health.
Please share your thoughts on these resilient actresses and their health journeys in the comments.


